Have you ever wondered about your IVF pregnancy . . . ?

In Vitro Fertilization has been practiced worldwide for almost 30 years and more than four million babies have been born through this technology. Close follow-up of pregnancy outcomes has given us very reassuring evidence that IVF is a safe procedure.

Intracyctoplasmic sperm injection (ICSI) has also become a very successful technique for achieving pregnancy in cases of male factor infertility. Although it has been in use for 20 years, it is still important to collect long-term safety information about the children conceived through ICSI.

It has been suggested that there is an increase in the rate of chromosomal abnormalities among infertile men compared to the general population. As well, even men with normal chromosomes in their blood can have a 1.4 % to 17% risk of chromosomal abnormalities in their sperm.

Pacific Centre for Reproductive Medicine (PCRM) is collaborating with Dr. Sai Ma (University of British Columbia, Department of Obstetrics and Gynecology) in a study that is examining the incidence of chromosomal abnormalities in newborn babies from IVF, ICSI, and IUI treatment. The study will aim to estimate the possibility that ICSI may produce or transmit these chromosomal abnormalities. Also, this research will look at how such chromosomal problems occur.

You are being invited to participate in this important research because your pregnancy was conceived through IVF, ICSI, or IUI. Usually, once a baby is born, the umbilical cord and placenta are discarded. If you agree to participate in this study, blood from the umbilical cord and the placental tissue will be collected and sent to Dr. Ma for genetic and chromosomal analysis. In the unfortunate event that you were to have a miscarriage, the tissue could still be collected and sent to the regular embryopathology department for analysis.

This study is funded through the Canadian Institute for Health Research (CIHR).

If you would like more information about the study or to receive a detailed consent form, please contact Dr. Sai Ma at 604-875-2000 ext. 5686.