When a woman is born, her ovaries contain a lifetime supply of eggs. Each month, follicle stimulating hormone (FSH) stimulates a group of eggs to mature within the ovary. In response, the ovarian follicle produces estrogen, the principal sex hormone that regulates female reproductive organs. Some women with ovarian factor infertility experience a decline in egg quantity and quality long before they hit menopause, making it difficult for them to conceive.

What causes Ovarian Factor Infertility?

Failed or irregular ovarian function can be due to a variety of causes such as hormonal imbalances, environmental factors, conditions such as PCOS and hyperprolactinemia and stress. Treatments, such as radiation and chemotherapy, can also destroy ovarian tissue. In rare cases, a woman may be born without functioning ovaries or have a genetic disorder that predisposes her to premature ovarian failure.

How do I know if my ovarian function is declining?

Have your FSH levels tested. PCRM’s Clomiphene Citrate Challenge Test (CCCT) is used to predict how women with elevated FSH levels will respond to treatment with injections of FSH.